Measure your glucose level
Body acquires nutrients by digesting a food. Many enzymes, hormones and other
substances are involved. Fructose, glucose and galactose are final products of
carbohydrate digestion, whereas glucose has circa 80% share of these. Once
absorbed from the intestinal tract, liver rapidly converts fructose and galactose
into glucose. Glucose is a primary fuel for the cells. However, most cells need
insulin to convert glucose into an energy. Therefore, it is possible to say that
insulin lowers blood glucose level. Contratry, glucagon raises blood glucose
level by stimulating a breakdown of glycogen. Glycogen is a polymer store of
glucose. Pancreas releases glucogon once it senses low blood glucose level.
There is an insulin deficit with type 1 and 2 diabetics. For this reason,
glucose accumulates in various organs. This damages the organs. Especially,
type-1 diabetic has to dose insulin regularly. Insuline dose must correspond
with current blood glucose level. An over-dose could kill the patient shortly
by lowering blood glucose level too much - hypoglycemic shock.
Among other effects, needed amount of glucose depends on diet and physical
activity. Therefore, needed amount of insulin varies through the day and the
insulin dose has to be adjusted. Otherwise, hyper- or hypoglycemic shock may
ensue. These are acute complications ( blood glucose level is either too high
or too low), which may lead to death shortly.
Through the day, the diabetic patient must self-monitor blood glucose level.
Patient draws a drop of blood. Then. a glucometer determines blood glucose
level of this drop. Common patients draws 2-3 drops a day. Such a low
frequency cannot capture all important events.
For a frequent monitoring of glucose level, there is a continuous glucose
monitoring system (CGMS). By diabetologist's recommendation, diabetic patient
wears CGMS about one week. CGMS records glucose level every five minutes.
However, it measures glucose level of subcutaneous tissue, not blood glucose
level. In the subcutaneous tissue, there is a CGMS sensor installed. The
sensor transmitts data to a receiver that actually stores the data. It is
possible to export these data from the reciever, to utilize them later.
Respective software can store the data as a single file in a computer.
CGMS can be paired together with an insulin pump. In such case, the pump
doses insulin based on measured glucose level of subcutaneous tissue. For
an optimal function, it would be necessary to dose insulin based on blood
glucose level. However, determining blood glucose level from CGMS data is
not a trivial problem. As our model solves this problem, you can test it
with this portal in the practice.
Our portal visualizes measured glucose level. Thanks to our model of
glucose dynamics, it is also possible to visualize the calculated blood
glucose level. If you have CGMS data, you can try it. Feel free to ask
your physician or
Registered user can upload the data, browse and review them as needed
once logged-in. If you do not wish to register, it is possible to upload
the data anonymously. However, it is not possible to get back to these
data once the web page is closed.